LIBRIUM is a real drug EQUILIBRIUM just does not, to me, really get to the point. Accessed Nov.Yeah, I know that that's why the name of the film was changed. Selective serotonin reuptake inhibitors: Pharmacology, administration, and side effects. Antidepressant-associated sexual dysfunction: impact, effects, and treatment. Timing of onset of antidepressant response with fluoxetine treatment.
Nierenberg AA, Farabaugh AH, Alpert JE, et al. Sexual side effects can be ongoing if not addressed by your healthcare provider. In most people, these side effects will start to subside in a few weeks. Prozac can be an “activating” antidepressant and can lead to side effects in the first few weeks that may impact your response, such as insomnia (trouble sleeping), anxiety or nervousness. Research has shown that over half of patients (55.5%) who respond to Prozac treatment for depression will start responding by the second week. A depressed mood can take up to 8 weeks to fully respond. Your sleep, energy and appetite may improve over the first month and you may have a better focus on daily tasks. Within the first one to two weeks, most people feel lower levels of anxiety, restlessness or tiredness with Prozac treatment. Related: Prozac side effects (in more detail) Bottom Line Speak to your healthcare provider about any side effects that do not subside over time, as dosage adjustments or other treatment options may be possible. Weight gain is not a common side effect with Prozac treatment, and some patients may lose weight, although this can be temporary. However, sexual side effects (such as decreased libido, lack of orgasm, delay in ejaculation, impotence) can be an ongoing side effect and has been reported in up to 50% of patients. Many of these side effects will go away within a week or two. Prozac is frequently associated with insomnia, headache, agitation and sexual dysfunction. The most common side effects with Prozac (in at least 10% of patients) include: You probably will not experience all of the side effects reported with Prozac. What side effects occur in the first week with Prozac?Īll selective serotonin reuptake inhibitors are associated with various side effects, many of which are similar. It comes an oral capsule and is taken once per day in the morning. and a month's supply of fluoxetine usually costs less than $10.00. It is available as a generic option in the U.S. It is a commonly used, widely available and affordable SSRI treatment. Prozac is approved by the FDA to treat major depressive disorder, obsessive compulsive disorder (OCD), panic disorder, bulimia nervosa (an eating disorder), and premenstrual dysphoric disorder (PMDD). It works by increasing levels of a chemical (neurotransmitter) in your brain called serotonin. Yes, Prozac (generic name: fluoxetine) is in the selective serotonin reuptake (SSRI) class of antidepressants. However, in patients without a response to Prozac by week 4 to 6, there was a 73% to 88% chance there would be no response by week 8. By week six, the probability of having a response to Prozac treatment (20 mg/day) was 90%. Over half of the patients (55.5%) responded by week two, 24.7% by week five and 9.3% (35 patients) by week six. A sustained response was defined as a 30% decrease on the depression scale from the start of the study which led to a 50% reduction by week 8. Patients were assessed using the 17-item Hamilton Depression Rating Scale every 2 weeks, a common measure used in depression studies. 
Researchers evaluated the time until the start of an antidepressant sustained response with fluoxetine (Prozac) treatment given at 20 mg/day in an 8-week study of 182 patients with major depression.How soon will I notice Prozac working?Ĭlinical research has shown that over half of patients (55.5%) who respond to Prozac (fluoxetine) for depression will start responding by the second week of treatment. Do not stop taking Prozac without speaking to your doctor first. Results are individual, but call your healthcare provider if you have side effects that make you want to stop treatment.
Side effects, like trouble sleeping, agitation, headache or stomach upset are usually temporary and will often subside within the first month of treatment. A depressed mood can take 6 to 8 weeks to fully respond to treatment. Some people may start to feel results in 1 to 2 weeks, while others may take up to 8 weeks or longer to feel the effects.Most people feel lower levels of anxiety, restlessness and tiredness when Prozac first starts to work.
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